Eskisehir Osmangazi University Eskisehir Vocational School was established in 2010 in cooperation with ESOGU and Eskisehir Chamber of Industry (ESO) in Eskisehir Organized Industrial Zone (EOSB). The foundation of the Eskisehir Vocational School, which has a closed area of ​​3300 m2 and an open area of ​​16500 m2, was laid in May 2011 and its building was completed in December. Environmental Protection Control and Mechatronics Programs were opened in the Department of Technical Programs in 2011 and in the 2012-2013 academic year, Mechatronics and Environmental Protection Control programs started their first students' education life. The Machine program was opened in 2013 and the Machine program started its education life in the 2013-2014 academic year. There are 8 classrooms of 50 m2, 4 laboratories of 100 m2, teaching rooms in 448 m2, 80 m2 library area, 50 m2 meeting room and 40 m2 internet hall on the campus of ESOGU-ESKİSEHİR MYO-ESOB. There is a 350 m2 dining hall for 250 people in ESOGU-ESKİSEHİR MYO ESOB building. These areas are capable of supporting 4 programs.

Eskişehir Organized Industrial Zone, where 542 companies produce and employ more than 43 thousand employees, is 10 km away from the city center. In addition, there are sports facilities, fairground, KOSGEB, technology center, logistics center ABİGEM, auto-producer electricity production, eso-es.net service provider, business and trade center, CNC training center, etc. at EOSB.